Genome structural variation for 100 tomatoes
نویسندگان
چکیده
منابع مشابه
Structural variation of the human genome.
There is growing appreciation that the human genome contains significant numbers of structural rearrangements, such as insertions, deletions, inversions, and large tandem repeats. Recent studies have defined approximately 5% of the human genome as structurally variant in the normal population, involving more than 800 independent genes. We present a detailed review of the various structural rear...
متن کاملHuman Genome Structural Variation January 23 , 2006
Rationale. The last three years have brought considerable progress in understanding the nature and patterns of single nucleotide polymorphism within the human species. Of the estimated 10-15 million common SNPs, a large fraction have already been discovered and 3.8 million SNPs converted to genotyping assays, providing the community with a framework to investigate associations between common SN...
متن کاملStructural variation in the human genome.
Genomic structural variation is generally defined as deletions, insertions, duplications, inversions, translocations or copy number variation (CNV) in large DNA segments (>1 kb). The structural variation in an individual genome includes thousands of discrete regions, spans millions of base pairs, and encompasses numerous entire genes and their regulatory regions. This results in missing or chan...
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Summary: Current strategies for SNP and INDEL discovery incorporate sequence alignments from multiple individuals to maximize sensitivity and specificity. It is widely accepted that this approach also improves structural variant (SV) detection. However, multisample SV analysis has been stymied by the fundamental difficulties of SV calling, e.g. library insert size variability, SV alignment sign...
متن کاملPrimate genome architecture influences structural variation mechanisms and functional consequences.
Although nucleotide resolution maps of genomic structural variants (SVs) have provided insights into the origin and impact of phenotypic diversity in humans, comparable maps in nonhuman primates have thus far been lacking. Using massively parallel DNA sequencing, we constructed fine-resolution genomic structural variation maps in five chimpanzees, five orang-utans, and five rhesus macaques. The...
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ژورنال
عنوان ژورنال: Nature Food
سال: 2020
ISSN: 2662-1355
DOI: 10.1038/s43016-020-0125-7